Job Information
MCW: SARGEANT HEALTH CENTER Postdoctoral Fellow in MILWAUKEE, Wisconsin
JOB REQUIREMENTS: Position Description: Every day, in ways both big and small, the Medical College of Wisconsin (MCW) is impacting lives for the better. MCW ... changemaking for a healthier Wisconsin. In the role of Postdoctoral Fellowyou will beworking in Cell Biology, Neurobiology and Anatomy. Purpose A Postdoctoral Fellow position is available in the Department of Cell Biology, Neurobiology, and Anatomy in the lab of Dr. Brian Lin to study the therapeutic efficacy and underlying mechanisms of cation channel blockers to treat heart disease, with a focus on dystrophic cardiomyopathy in Duchenne muscular dystrophy. We use a variety of mouse models in vivo and human stem cell models in vitro to study treatments for DMD. We apply biophysical measurements of individual cardiac muscle cell contraction and ion transients to determine underlying mechanisms of disease and identify new therapies. We welcome motivated, and organized candidates who can work independently in a basic research laboratory setting. Ideal candidates will have a research backgrounds in any combination of the following: cardiac physiology, animal modeling, stem cell engineering, molecular biology techniques (e.g. qPCR and Western blotting), transcriptomics/proteomics or single cardiomyocyte biophysics. Our lab ethos is that anyone can learn, and we will provide appropriate training to further develop the skillsets of trainees. Primary Functions Measure contractile and ion transient kinetics of individual cardiac cells Design, organize, and run a preclinical trials in mouse models of heart disease, and detailed tracking of all animals enrolled Design and run preclinical trials-on-a-chip in human stem cell derived models of heart disease Detect gene expression and protein expression using traditional biomolecular methods (qPCR and Western blotting) Determine signaling pathways using gene set enrichment or Ingenuity pathway analysis of transcriptomic datasets Proficient in scientific data management and analysis platforms (e.g. GraphPad Prism) Participate in collaborations and communication with the principal investigators and fellow scientists Participate in regular one-on-one and lab meetings with principal investigator and research staff and evaluate/interpret the validity of data, develop methodologies, evaluate lab procedures Participate in departmental meetings and national meetings by presenting research progress Knowledge - Skills - Abilities Applicants should have extensive experience with common lab techniques such as qPCR, Western blotting, and cell culture. Experience with animal handling, cell and molecular biophysics are... For full info follow application link. EEO/AA Minorities/Females/Vets/Disability The Medical College of Wisconsin is an affirmative action/equal opportunity employer and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, veteran status, disability or sexual orientation. ***** APPLICATION INSTRUCTIONS: Apply Online: ipc.us/t/0BE39B75BEF24316 Qualified females, minorities, and special disabled veterans and other veterans are encouraged to apply.