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JOB DESCRIPTION

Postdoctoral Fellow in Computational Biology

The Mount Sinai Center for Transformative Disease Modeling (MSCTDM) is looking for a talented and motivated Postdoc Fellow in computational biology for projects at the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai.

The MSCTDM aims to develop novel insights on critical biological networks underlying the onset and progression of complex, multifactorial diseases, including Alzheimer’s disease (AD). Specifically, we are developing and using cutting-edge machine-learning and artificial intelligence technologies to integrate bulk and single cell multi-omics data, imaging features, small molecule drug libraries, and clinical information into integrative analytical models. In parallel, we are developing in vitro and in vivo experimental models to validate molecular drivers predicted by our multiscale network models of diseases as well as novel therapeutics developed from our AI-aided systems pharmacology approaches. Together, we offer an excellent multidisciplinary scientific network environment and outstanding research and training opportunities with access to state-of-the-art facilities for our faculty and staff to thrive in their careers in academia and industry.

RESPONSIBILITIES

Key tasks and responsibilities

A successful candidate will be part of a team of leading computational and experimental biologists to develop novel tools, methodologies, and strategies towards the integration of critical disease-related biological network models for biomarker, mechanism and therapeutics discoveries. The postdoc will integrate large scale brain imaging and functional genomic data to predict and characterize Alzheimer's disease (AD) using machine learning and statistic approaches. Specific responsibilities/duties include: 1) analysis of brain magnetic resonance, diffusion tensor, slice imaging data; 2) integration of brain imaging data with genetics and functional genomics data using network models; 3) prediction of AD initiation and progression; 4) prepare manuscripts for publication; and 5) present research at academic conferences.

QUALIFICATIONS

Job requirements

• Ph.D. or equivalent doctoral degree in statistics, bioinformatics, computational biology, computer science, or related fields.

• Skilled in programming in R.

• Strong experience in brain imaging data analysis.

• Experience in analyzing next generation sequencing data.

• Ability to work in a multidisciplinary team.

• Knowledge about neurodegenerative diseases, especially Alzheimers disease.

SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 816 - Genetics/Genomic Sci - ISM, Icahn School of Medicine

EOE Minorities/Women/Disabled/Veterans

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism.

ABOUT US

Strength Through Diversity

The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:

• Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential.

• Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination.

• Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.

At Mount Sinai, our leaders strive to learn, empower others, and embrace change to further advance equity and improve the well-being of staff, patients, and the organization. We expect our leaders to embrace anti-racism, create a collaborative and respectful environment, and constructively disrupt the status quo to improve the system and enhance care for our patients. We work hard to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to advance professionally.

Explore more about this opportunity and how you can help us write a new chapter in our history!

“About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism.”

EOE Minorities/Women/Disabled/Veterans

Requisition ID : 3016067