Job Information
Rutgers The State University Postdoctoral Fellow (Valvezan Lab) in Piscataway, New Jersey
Position Details
| Recruitment/Posting Title | Postdoctoral Fellow (Valvezan Lab) |
|---|---|
| Job Category | Staff & Executive - Research (Laboratory/Non-Laboratory) |
| Department | RWJ-CABM |
| Overview | New Jersey's academic health center, Rutgers Biomedical and Health Sciences (RBHS) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University-New Brunswick and collaborating university wide, RBHS includes eight schools, a behavioral health network, and five centers and institutes that focus on cancer treatment and research, neuroscience, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research.Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers.Our clinical and academic facilities are located throughout the state-at Rutgers University-New Brunswick, including Piscataway; and at locations in Newark, Scotch Plains, Somerset, Stratford, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, Newark's University Hospital in Newark, and other affiliates.Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives. |
| Posting Summary | Rutgers, The State University of New Jersey, is seeking a Postdoctoral Fellow for the department of Pharmacology in the Center for Advanced Biotechnology and Medicine (CABM).The Valvezan lab studies how metabolic networks are coordinated to promote cell growth, and how to leverage that understanding to exploit metabolic dependencies in cancer. We recently discovered that the activity of the master metabolic regulator Mechanistic Target of Rapamycin Complex 1 (mTORC1), oscillates throughout the cell cycle with important functional consequences for cell growth and proliferation (https://www.biorxiv.org/content/10.1101/2024.02.06.579216v1). We seek a postdoctoral fellow to study how metabolism is differentially regulated throughout the cell cycle, and whether there are cell cycle phase-specific metabolic vulnerabilities that can be exploited in cancer. We discovered a targetable metabolic vulnerability that is induced downstream of mTORC1 in cancer, and can be exploited using clinically approved therapeutics to selectively kill cancer cells that have uncontrolled mTORC1 activation (https://pubmed.ncbi.nlm.nih.gov/29056426/, https://pubmed.ncbi.nlm.nih.gov/32271165/). We seek a Postdoctoral Fellow to determine the full translational potential of this potent vulnerability in human cancers.The Postdoctoral Fellow will work at the interface of basic and translational science, combining genetic, pharmacological and molecular biology/biochemistry approaches with the latest metabolomics, metabolic flux analysis, and expression profiling assays in cultured cells and mouse tumor models to gain a comprehensive understanding of how signaling pathways remodel cellular metabolism and how to leverage these insights for therapeutic benefit. For more information, including detailed project descriptions, please contact Dr. Alexander Valvezan at valvezan@cabm.rutgers.edu and visit the lab website: https://sites.rutgers.edu/valvezan-lab/research/Among the key duties of this position are the following:
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| Position Status | Full Time |
| Hours Per Week | |
| Daily Work Shift | Day |
| Work Arrangement | This position requires a fully on-site work arrangement. |
| FLSA | Exempt |
| Grade | 99S |
| Position Salary | |
| Annual Minimum Salary | 0.000 |
| Annual Mid Range Salary | 0.000 |
| Annual Maximum Salary | 0.000 |
| Standard Hours | 37.50 |
| Union Description | AAUP |
| Payroll Designation | PeopleSoft |
| Benefits | Rutgers offers a comprehensive benefit program to eligible employees. For details, please go to http://uhr.rutgers.edu/benefits/benefits-overview. |
| Seniority Unit | |
| Terms of Appointment | Staff - 12 month |
| Position Pension Eligibility | ABP |
| Minimum Education and Experience |
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|---|---|
| Certifications/Licenses | |
| Required Knowledge, Skills, and Abilities | |
| Preferred Qualifications |
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| Equipment Utilized | |
| Physical Demands and Work Environment |
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| Special Conditions |
| Posting Number | 24ST1494 |
|---|---|
| Posting Open Date | |
| Special Instructions to Applicants | |
| Regional Campus | Rutgers Biomedical and Health Sciences (RBHS) |
| Home Location Campus | Piscataway (RBHS) |
| City | Piscataway |
| State | NJ |
| Location Details |
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.
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